Tuesday, January 31, 2012

Study Looks at Possible HIV Drugs-Birth Defect Link (HealthDay)

MONDAY, Jan. 30 (HealthDay News) -- Pregnant women with HIV can prevent passing the AIDS-causing virus to their babies by taking antiretroviral drugs, but there remains a possibility that some of these medications might cause birth defects, such as cleft lip and palate, according to a new study.

Antiretroviral drugs have been found to reduce the risk of mothers passing HIV on to their children from between 15 and 25 percent to less than 1 percent. These drugs, however, are still under investigation and not considered safe during pregnancy, the study authors noted.

To analyze the possible association between antiretroviral drugs and birth defects, Vassiliki Cartsos, an associate professor and director of graduate orthodontics at Tufts University School of Dental Medicine in Boston, and colleagues examined five years of adverse events compiled by the U.S. Food and Drug Administration.

Their findings are published in the January issue of Cleft Palate--Craniofacial Journal.

The investigators found seven antiretroviral drugs were associated with 26 incidents of cleft lip and palate. However, the authors noted, uncovering an association does not prove a cause-and-effect relationship.

In other words, although the study findings should serve as a red flag, the researchers pointed out that the findings do not confirm that the antiretroviral drugs caused the birth defects.

Those drugs included lamivudine (Epivir); efavirenz (known as EFV); nelfinavir (Viracept); and the combination of abacavir (Ziagen), sulfate, lamivudine and zidovudine (Retrovir).

The study authors concluded in a journal news release that more research is needed to determine if there is a link between antiretroviral drugs and cleft lip and palate, a congenital malformation believed to have several causes, including genetic and environmental factors.

More information

The World Health Organization has more about antiretroviral therapy.

Source: http://us.rd.yahoo.com/dailynews/rss/health/*http%3A//news.yahoo.com/s/hsn/20120131/hl_hsn/studylooksatpossiblehivdrugsbirthdefectlink

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Officers checking robbery find 5 dead in Ala. home (AP)

BIRMINGHAM, Ala. ? Police investigating a possible robbery at a Birmingham home early Sunday instead found five people dead inside, authorities said.

Birmingham Police Sgt. Johnny Williams said officers arrived at the house around 3:30 a.m. Sunday after getting a call that a robbery was in progress and soon discovered the five victims. He told reporters that investigators are interviewing potential witnesses but so far have made no arrests.

"Someone out there knows more information," said Williams. "We know someone is going to do the right thing."

The victims' identities and the causes of death were not immediately released. Birmingham authorities launched a homicide investigation and police believe more than one person was involved.

"It obviously appears to us this horrific crime was not a random act of violence," said Birmingham Police Chief A.C. Roper.

The two-bedroom house, which is made partly of cinderblocks, was built along a busy street in west Birmingham. Vacant homes sit beside houses where some residents have lived for years. One is Beatrice Houston, who lives across the street from the home where the bodies were found.

Houston, who is 64, said she believes a woman, her son and her brother had lived in the house for the last year or so. She said she didn't know the neighbors' names, but started worrying when she saw groups of young men hanging around the house at odd hours.

Still, she said, her neighbors didn't cause many disturbances.

"I never had any problem with them," she said. "They were cordial. I just kept to myself."

Doreatha Moss lived in the house, a white building with green trim now surrounded by police tape, until late 2010. She doesn't know who moved in to take her place.

"I don't know anything about it now other than that there's all the time a bunch of young guys hanging around there," said Moss, who still returns to visit friends. "That's not good."

Houston said most of her neighbors are still in a "state of shock"

"They never had any trouble over there," Houston said. "I never seen the police over there. This was really strange that this happened. It wasn't like they were real rowdy."

___

Associated Press writer Greg Bluestein in Atlanta contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/ap/20120130/ap_on_re_us/us_five_dead_alabama

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Monday, January 30, 2012

Japan population to shrink by one-third by 2060 (AP)

TOKYO ? Japan's population of 128 million will shrink by one-third and seniors will account for 40 percent of people by 2060, placing a greater burden on a smaller working-age population to support the social security and tax systems.

The grim estimate of how rapid aging will shrink Japan's population was released Monday by the Health and Welfare Ministry.

In year 2060, Japan will have 87 million people. The number of people 65 or older will nearly double to 40 percent, while the national work force of people between ages 15 and 65 will shrink to about half of the total population, according to the estimate, made by the National Institute of Population and Social Security Research.

The total fertility rate, or the expected number of children born per woman during lifetime, in 2060 is estimated at 1.35, down from 1.39 in 2010 ? well below more than 2 needed to keep the country's population from declining. But the average Japanese will continue to live longer. The average life expectancy for 2060 is projected at 90.93 for women, up from 86.39 in 2010, and 84.19 years for men, up from 79.64 years.

Prime Minister Yoshihiko Noda has pledged to push for social security and tax reforms this year. A bill he promised to submit by the end of March would raise the 5 percent sales tax in two stages to 8 percent in 2014 and 10 percent by 2015, although opposition lawmakers and the public pose challenges to its approval.

The institute says Japan has been the world's fastest aging country, and with its birthrate among the lowest, its population decline would be among the deepest globally in coming decades.

Experts say that Japan's population will keep losing 1 million every year in coming decades and the country urgently needs to overhaul its social security and tax system to reflect the demographic shift.

"Pension programs, employment and labor policy and social security system in this country is not designed to reflect such rapidly progressing population decline or aging," Noriko Tsuya, a demography expert at Keio University, said on public broadcaster NHK. "The government needs to urgently revise the system and implement new measures based on the estimate."

Source: http://us.rd.yahoo.com/dailynews/rss/japan/*http%3A//news.yahoo.com/s/ap/20120130/ap_on_re_as/as_japan_population

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EU rejects call for control over Greek budget (AP)

BRUSSELS ? The European Union's executive body is rejecting calls from Germany to establish a eurozone budget commissioner who would directly control tax and spending decisions in debt-ridden Greece.

The European Commission said Saturday that "executive tasks must remain the full responsibility of the Greek government, which is accountable before its citizens and its institutions."

The Commission, the European Central Bank, and the International Monetary Fund already have unprecedented powers over Greek spending, after negotiating with Athens stringent austerity measures and economic reforms in return for a first, multi-billion euro bailout.

They are reviewing implementation of these measures and discussing a second bailout.

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/ap/20120128/ap_on_bi_ge/eu_europe_financial_crisis

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Saturday, January 28, 2012

Video: Researchers show how viruses evolve, and in some cases, become deadly

Friday, January 27, 2012

In the current issue of Science, researchers at Michigan State University demonstrate how a new virus evolves, which sheds light on how easy it can be for diseases to gain dangerous mutations.

The scientists showed for the first time how the virus called "Lambda" evolved to find a new way to attack host cells, an innovation that took four mutations to accomplish. This virus infects bacteria, in particular the common E. coli bacterium. Lambda isn't dangerous to humans, but this research demonstrated how viruses evolve complex and potentially deadly new traits, said Justin Meyer, MSU graduate student, who co-authored the paper with Richard Lenski, MSU Hannah Distinguished Professor of Microbiology and Molecular Genetics.

"We were surprised at first to see Lambda evolve this new function, this ability to attack and enter the cell through a new receptor ? and it happened so fast," Meyer said. "But when we re-ran the evolution experiment, we saw the same thing happen over and over."


Researchers at Michigan State University demonstrate how a new virus evolves, shedding light on how easy it can be for diseases to gain dangerous mutations. Credit: Michigan State University/Jeremy Polk, National Science Foundation

This paper follows recent news that scientists in the United States and the Netherlands produced a deadly version of bird flu. Even though bird flu is a mere five mutations away from becoming transmissible between humans, it's highly unlikely the virus could naturally obtain all of the beneficial mutations all at once. However, it might evolve sequentially, gaining benefits one-by-one, if conditions are favorable at each step, he added.

Through research conducted at BEACON, MSU's National Science Foundation Center for the Study of Evolution in Action, Meyer and his colleagues' ability to duplicate the results implied that adaptation by natural selection, or survival of the fittest, had an important role in the virus' evolution.

When the genomes of the adaptable virus were sequenced, they always had four mutations in common. The viruses that didn't evolve the new way of entering cells had some of the four mutations but never all four together, said Meyer, who holds the Barnett Rosenberg Fellowship in MSU's College of Natural Science.

"In other words, natural selection promoted the virus' evolution because the mutations helped them use both their old and new attacks," Meyer said. "The finding raises questions of whether the five bird flu mutations may also have multiple functions, and could they evolve naturally?"

###

National Science Foundation: http://www.nsf.gov

Thanks to National Science Foundation for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/117147/Video__Researchers_show_how_viruses_evolve__and_in_some_cases__become_deadly

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Finance chiefs reassure CEOs over European crisis (AP)

DAVOS, Switzerland ? Leading finance chiefs sought to reassure anxious global business leaders on Friday that Europe is on track to solve its crippling debt crisis before it drags the world's economies down. Europe's top banker said investors, burned after trusting the region's governments too much, now trust them too little.

The finance chiefs said the picture in Europe has changed over the past two months as the European Central Bank has loaned billions of euros to fragile banks, indebted countries have pushed through convincing reforms and EU leaders have come near to building a closer fiscal union that would make their common currency stronger.

Several also signaled Friday that Greece is close to clinching a crucial debt-reduction deal with private bondholders ? a key element in Europe's efforts to stem a two-year debt crisis that is causing ripples around the globe. The crisis is a central topic at the World Economic Forum, a gathering of government and business leaders at the Swiss ski resort of Davos.

"They're making progress on reforms, they're changing the institutions of Europe to put better discipline on fiscal policy," said U.S. Treasury Secretary Timothy Geithner. "You have three new governments doing some very tough things. You have an ECB doing what central banks have to do. You see them move to try to strengthen the financial sector."

Mario Draghi, head of the European Central Bank, said a combination of actions ? including super-cheap, long-term loans to shaky banks on the continent and a couple of interest rate cuts ? have helped Europe avoid deeper financial trouble.

"We have avoided a major credit crunch, a major lending crisis," he said.

Draghi said borrowing rates would remain high "for quite a while" because bond markets are overestimating the risk involved in holding European government debt after years of underestimating it. But he called market pressure "the most potent engine for reform in different governments."

Geithner said the fate of the U.S. economy ? and by extension of the rest of the world ? hinges on Europe's debt crisis, along with potential tensions with Iran. He said the main piece of unfinished business for Europe is building a bigger fund to help troubled economies survive.

But while French Finance Minister Francois Baroin said that fund needs to be increased to calm markets, his German counterpart, Wolfgang Schaeuble, indicated that his government is not prepared to do so. Germany, as Europe's biggest economy, would face the biggest bill.

"We must not give the wrong incentives," Schaeuble said. "You can make any figure. It will not work if the real problems will not be solved."

Both, together with Spanish Economy Minister Luis de Guindos Jurado and European Monetary Affairs Commissioner Olli Rehn, agreed that the idea of issuing "eurobonds" backed jointly by all eurozone governments is a nonstarter for now. They didn't rule out the possibility that such bonds could be introduced once confidence in Europe's public finances is restored, with Guindos calling that a "final target."

Schaeuble said eurobonds would provide bad incentives by allowing debt-ridden countries to "spend money you don't have on the bill of others."

Many economists have said eurobonds are needed to solve the crisis as they could reduce the borrowing costs of heavily indebted countries by pooling them with bonds of stronger economies like Germany's.

Professor Nouriel Roubini, the renowned economist who predicted the financial crash of 2008, is one who thinks that eurobonds have to form part of a eurozone strategy to fend off the possibility of a breakup.

The eurozone "could be a slow-motion train wreck," Roubini said.

Europe has been grappling with the crisis ever since Greece conceded at the end of 2009 that its public finances were in far worse shape than previously thought. Greece remains at the epicenter of the crisis over two years later. Its borrowing costs remain too high for it to borrow in the markets so a second European-led bailout is in the offing.

The finance chiefs signaled Friday that a deal is at hand that could help ease some of the near-term tensions.

Greece has been negotiating with the a group representing banks and other lenders in the hopes that they will forgive half of Greece's debt in exchange for Greek assurances that it will pay back the other half without defaulting on its loans. The deal would also let Greece repay over a longer period at a lower interest rate ? negotiators have been trying to agree on what that rate will be.

Schaeuble said he is "quite optimistic" about a deal, while Rehn said he hopes a deal can be reached "if not today, maybe by the weekend."

Agreement between Greece and its creditors is needed before Europe and the International Monetary Fund agree to a second multibillion-euro bailout package.

At the heart of the problem is that the 17 countries that use the euro use a single currency but have different fiscal policies. That changes the nature of their debt, said Adair Turner, chairman of Britain's banking regulator the Financial Services Authority.

"That debt is more equivalent to the State of California debt than the U.S. federal debt," he said.

That's why all but one of the 27 EU countries ? the United Kingdom has refused to participate ? are discussing a closer fiscal union. On Monday, leaders meet in Brussels to work out the details of that new compact.

Schaeuble and Baroin noted that even the agreement in principle to forge closer ties has calmed markets since a December summit, as borrowing rates have dropped and stock markets have risen.

"It's amazing," Draghi said. "If you compare today with even five months ago, the euro area is another world."

The crisis threatens more than Europe: the U.N.'s refugee chief warned Friday that it is fueling conflicts around the world. Antonio Guterres told The Associated Press that rising food prices and growing unemployment are hitting those already at the bottom hardest, sparking conflict in places like South Sudan and exacerbating hotspots including Afghanistan, Iraq and Somalia.

_____

Frank Jordans and Edith Lederer in Davos and David McHugh in Frankfurt, Germany contributed to this story.

Source: http://us.rd.yahoo.com/dailynews/rss/business/*http%3A//news.yahoo.com/s/ap/20120127/ap_on_bi_ge/eu_davos_forum

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Friday, January 27, 2012

AP Interview: Coe defends Olympic ticketing

Former British Olympic champion Sebastian Coe poses next to an ice sculpture to promote the 2012 Summer Olympic Games on the sideline of the World Economic Forum in Davos, Switzerland, Thursday, Jan. 26, 2012. The ice sculpture represents London's Tower Bridge, Big Ben, Canary Wharf and the London Eye. (AP Photo/Michel Euler)

Former British Olympic champion Sebastian Coe poses next to an ice sculpture to promote the 2012 Summer Olympic Games on the sideline of the World Economic Forum in Davos, Switzerland, Thursday, Jan. 26, 2012. The ice sculpture represents London's Tower Bridge, Big Ben, Canary Wharf and the London Eye. (AP Photo/Michel Euler)

Mayor of London Boris Johnson, left, and former British Olympic champion Sebastian Coe, right, speak to the media next to an ice sculpture to promote the 2012 Summer Olympic Games on the sideline of the World Economic Forum in Davos, Switzerland, Thursday, Jan. 26, 2012. The ice sculpture represents London's Tower Bridge, Big Ben, Canary Wharf and the London Eye. (AP Photo/Michel Euler)

Mayor of London Boris Johnson, left, British Prime Minister David Cameron, center, and former British Olympic champion Sebastian Coe, right, arrive on stage during a session at the World Economic Forum in Davos, Switzerland, Thursday, Jan. 26, 2012. British Prime Minister David Cameron backed the idea of a free trade deal between the European Union and the U.S. on Thursday, suggesting that a transatlantic pact could deliver a much-needed boost to global commerce. (AP Photo/Michel Euler)

(AP) ? The cost of staging the London Olympics remains within budget and glitches in the ticketing process are being ironed out before the next batch go on sale in April, organizing committee chief Sebastian Coe said Thursday.

In an interview with The Associated Press six months before the games, the two-time 1,500-meter Olympic champion defended his organization against charges that ticket sales have been flawed from the very beginning.

Last year, organizers put the first batch of tickets on sale via a complicated ballot system. Many customers were left empty-handed and others ended up with far fewer tickets than they had hoped and often not the ones they had wanted.

"We've done it in bigger numbers than anything on the planet," Coe said.

Coe said he had three objectives during the ticketing process ? making sure the venues were full throughout the games, that a large chunk of the tickets were sold at affordable prices and that his committee raised a quarter of its 2 billion pound ($3.1 billion) private operating budget.

About 1.9 million people made 24 million ticket applications for the 6 million tickets available through the ballot. Many people want to offload tickets they garnered through the ballot and the London organizers created a resale website to allow that to happen. However, the site, operated by Ticketmaster, was unable to cope with the traffic and was shut down within hours of launching earlier this month.

Though the site has now reopened to allow customers to sell unwanted tickets, prospective buyers won't be able to purchase any until April.

"On the first day it didn't work as well as we wanted it to work," Coe said. "This was something we weren't satisfied with."

London's preparations for the games, which begin on July 27, have been relatively smooth. Coe insisted that the cost of hosting the 16-day sporting spectacle remains within budget. The government's public sector budget for the games, which includes all the venue construction and infrastructure projects, totals 9.3 billion pounds ($14.5 billion).

"We will maintain a balanced budget to the completion of the project and the infrastructure will be delivered within the budget that has already been agreed by government," Coe said. "Occasionally some things are slightly more than you expect. On a lot of occasions they're slightly less than you expect, but overall those changes have taken place within that 9.3 billion pound envelope."

Earlier Thursday, Sky Sports News projected that the final cost for the games will be over 12 billion pounds ($18 million) and could even reach 24 billion pounds ($37 billion). The British broadcaster said costs are rising because of a number of factors, including more anti-doping control officers, money for local councils for their Olympic torch relay programs and paying Underground workers not to strike.

With the finishing line in sight, Coe said London will increasingly begin to look like an Olympic city. He noted that the Olympic rings are already up at St. Pancras international train station and the commercial partners have started branding their buildings.

However, much of the focus over the final months will be spent making sure that everything has been tested thoroughly. Already three-quarters of the sports venues have been tested.

While conceding that many aspects of a smooth functioning of the games were outside the control of the organizing committee, Coe said relations with all involved players, including Transport for London, are smooth.

"We've got teams now working all their waking hours testing all these systems and it is very serious," Coe said. "I know as an athlete when I've been shortchanged at a championship because people clearly haven't tested systems. They've allowed me to waste a lot of time during the course of a day when I should be thinking of other things."

Coe declined to comment directly on Wednesday's resignation of a volunteer on the Olympics' sustainability commission over Dow Chemical Co.'s sponsorship of the games.

Campaigner Meredith Alexander said she was quitting the watchdog body to protest Dow's links to the deadly 1984 gas leak at a Union Carbide plant in the central Indian city of Bhopal, which killed an estimated 15,000 people. Activists have protested Dow's sponsorship of a decorative wrap that will encircle the Olympic Stadium.

While recognizing the "pain still felt around the disaster at Bhopal," Coe said Dow was not the owner or the operator of the plant at the time. Dow bought Union Carbide in 2000.

Critics argue that the purchase makes the U.S.-based company responsible for groundwater contamination and other issues that linger in India.

Bhopal victims' rights groups also have demanded the scrapping of the sponsorship deal, saying it would give undue publicity to a company they accused of refusing to clean up after itself.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-01-26-EU-Davos-Forum-Olympics/id-0c2750cc8d924bc59ad56b88ca9e6772

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Verizon Galaxy Nexus tagged at under $100 on Amazon

Verizon Galaxy Nexus 1

The Verizon Galaxy Nexus is now selling at a price of $99.99 on Amazon. Folks who have been looking for ?reasonable? excuses to grab a bite of Ice Cream Sandwich may probably find this deal hard to resist.

The seamless amalgamation of hardware and software aims to bring an enhanced mobile experience for Galaxy Nexus users. It dons a 4.65-inch HD Super AMOLED contour display offering resolutions of 1280 x 720p. This 4G LTE powered phone brings in speed besides serving as a mobile hotspot for up to 10 Wi-Fi enabled handsets. Under the hood, a 1.2GHz dual core processor can be found which comes backed by a 1GB RAM.

As for the snappers, this NFC enabled device has a 5MP primary camera and a 3MP front-facing one. The former inclusion is complete with AF, LED flash and 1080p video recording capabilities. These images and videos along with other content can be hoarded on the handset?s 32GB memory. Thanks to Ice Cream Sandwich, features such as Face Unlock, Android Beam and quick multi-tasking can be indulged in by users on the move.

Verizon Galaxy Nexus 2

Needless to say, potential owners will also have Google services such as the integration of Google+ and access to the Android Market at their disposal. Coming back to the device?s $99.99 price tag on Amazon, it essentially means a $200 drop for the Samsung Galaxy which is now selling on Verizon at $299. Dug up by Android Central, the Verizon Wireless Galaxy coming through Amazon will require potential users to enter into a new two-year contract.

As mentioned earlier, the Verizon Galaxy Nexus price detail spells out to be $99.99 on Amazon.

Source: http://www.techshout.com/mobile-phones/2012/27/verizon-galaxy-nexus-tagged-at-under-100-on-amazon/

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Thursday, January 26, 2012

The bumbling jihadi? Alleged terror backer guessed FBI was listening.

An Uzbekistan man living in Denver has been charged with supporting an overseas terror group. At one point, court documents show, he openly cursed the FBI agents he assumed were listening to his phone call with an apparent terrorist contact.

An Uzbekistan man living in Denver has been charged with attempting to provide material support to a militant Islamic group in his home country.

Skip to next paragraph

Jamshid Muhtorov was arrested Saturday at Chicago?s O?Hare International Airport prior to boarding a Polish Airlines flight to Istanbul.

Federal agents suspect Mr. Muhtorov was on his way to volunteer for a mission or missions to help the Islamic Jihad Union, an Uzbekistan-based militant group seeking to establish a government based on Islamic law.

Court documents filed in the case read at times more like a slapstick comedy than a deadly serious terror operation. The suspect and an alleged overseas terror contact overuse the word ?wedding? as a code word, and at one point jointly curse the FBI agents who they believe ? correctly ? are monitoring their every utterance.

At one point, Muhtorov?s wife threatens to take their children from Denver and go live with her mother ? in Kygyzstan.

When he tells her she must choose between her mother or him, she accuses him of choosing the alleged mission in Turkey over his wife and children.

Ultimately, the seriousness of the case is crystal clear. Last summer, according to an FBI affidavit, Muhtorov ?told his young daughter that he would never see her again; but, if she was a good Muslim girl, he will see her in heaven.?

The Islamic Jihad Union (IJU) has claimed responsibility for suicide-type bombings, including simultaneous attacks in July 2004 on the US and Israeli embassies and the Uzbekistani Prosecutor General?s Office in Tashkent.

The group was tied to a foiled bomb plot in Germany in September 2007 and has claimed responsibility for attacks in 2008 and 2009 against US and other coalition forces in Afghanistan.

The IJU is believed to have trained with and provided support to Al Qaeda. It has been listed since 2005 as a US-designated terror group.

According to court documents, federal agents have been watching Muhtorov for the past year after he contacted the administrator of a pro-IJU website.

They have also been monitoring his e-mail contacts with someone code named ?Abu Muhammad,? who officials suspect is an IJU facilitator.

In March 2011, three days after an e-mail exchange between Muhtorov and Abu Muhammad, Muhtorov received a telephone call from someone identified in court documents only as ?a known associate.?

Muhtorov told the associate that the ?wedding house? sends greetings. He read the associate a suspected message from the IJU, referring to the group as ?our guys over there.?

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/tl--fYsYfSw/The-bumbling-jihadi-Alleged-terror-backer-guessed-FBI-was-listening

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Geohot quits Facebook and joins new startup Backplane

Iconic iPhone hacker George Hotz was hired at Facebook a while back. That didn't seem to work out very long as he's no longer there. What's he up to these days? It appears he's back to hacking and coding. This time he's with a brand new startup as well.


Source: http://feedproxy.google.com/~r/TheIphoneBlog/~3/L5xYpI0NQNM/story01.htm

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Wednesday, January 25, 2012

Japan posts first annual trade deficit since 1980 (AP)

TOKYO ? Japan reported its first annual trade deficit since 1980 as it imported expensive energy to offset shortfalls caused by the devastating tsunami and manufacturers shifted production overseas to avoid the damage inflicted by the strong yen.

The 2.49 trillion yen ($32 billion) deficit for 2011 reflected a 2.7 percent decline in the value of Japan's exports to 65.55 trillion yen ($843 billion). In December, the trade balance was a deficit of 205.1 billion yen, according to the Ministry of Finance figures released Wednesday.

"It reflects fundamental changes in Japan's economy, particularly among manufacturers," said Hideki Matsumura, senior economist at Japan Research Institute. "Japan is losing its competitiveness to produce domestically."

"It's gotten difficult for manufacturers to export, so they're they've moved production abroad so that products sold outside the country are made outside the country," he said.

The yen's surge to record levels against the dollar and euro has made Japanese exports more expensive and also erodes the value of foreign earned income when brought home. Recently, Nissan Motor Co. and Panasonic Corp. have shifted some of their output to factories overseas.

At the same time, Japan is facing intense competition from South Korea, Taiwan and Singapore, where labor and production costs are cheaper.

Japanese manufacturers have been battered by a host of negatives in the past year. The tsunami temporarily disrupted the production of automobile makers and others. Weakness in the U.S. economy and Europe's debt problems and recent flooding in Thailand, where many Japanese automakers have assembly lines, also contributed to export declines.

Another major factor behind the figures was the impact of the expensive energy imports Japan turned to after the March disaster touched off a nuclear crisis and led the country to shut down, or not restart, a large portion of its reactors, said Martin Schulz, senior economist with the Fujitsu Research Institute.

He said pressure to import energy will continue to weigh heavily on Japan for the next year, but will subside as the country pursues greater efficiency measures.

Much of Japan's oil and natural gas is imported from the Middle East, with which Japan had a 10.88 trillion yen trade deficit last year, up 33 percent, figures showed.

Japan still has a trade surplus with the U.S., although that is shrinking. For 2011, exports exceeded imports by 4.10 trilion yen ($52.6 billion), down 8.2 percent from a year earlier. Exports to the U.S. declined 2.8 percent to 10.02 trillion yen during the year, while imports inched up 0.2 percent to 5.9 trillion.

Japan had a 1.57 trillion yen trade surplus with China for the year. A breakdown of figures showed a trade deficit with mainland China, but a big surplus with Hong Kong.

Trade with Germany was fairly balanced last year as imports grew nearly 10 percent to 1.86 trillion yen. Exports came to 1.87 trillion yen, giving Japan a relatively small trade surplus of 16 billion yen.

The turmoil in Europe and the U.S. has driven up the yen as global investors flock to the currency as a relative safe haven. The yen hit multiple historic highs against the dollar, and touched a record against the euro earlier this month as well.

The yen is trading at around 78 to the dollar recently, a level that is extremely painful for exporters. Five years ago, the dollar was trading above 120 yen.

Matsumura believes that Japan will likely log another trade deficit this year amid prospects for high energy prices and a persistently strong yen, but that renewed strength in the global and Asian regional economies could put Japan back into the black in 2013.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_bi_ge/as_japan_trade

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AP IMPACT: Meth fills hospitals with burn patients

This photo provided Jan. 10, 2012, by the Franklin County Sheriff?s Department shows firefighters battling a blaze from a shake-and-bake meth lab explosion Jan. 29, 2010, at a house in Union, Mo. The crude new method of making methamphetamine, by combining raw and unstable ingredients in a 2-liter soda bottle, poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment _ a burden so costly that it?s contributing to the closure of some burn units. (AP Photo/Franklin County Sheriff?s Department )

This photo provided Jan. 10, 2012, by the Franklin County Sheriff?s Department shows firefighters battling a blaze from a shake-and-bake meth lab explosion Jan. 29, 2010, at a house in Union, Mo. The crude new method of making methamphetamine, by combining raw and unstable ingredients in a 2-liter soda bottle, poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment _ a burden so costly that it?s contributing to the closure of some burn units. (AP Photo/Franklin County Sheriff?s Department )

This photo provided Jan. 10, 2012, by the Franklin County Sheriff?s Department shows shake-and-bake meth ingredients found at house that burned from a meth lab explosion Jan. 29, 2010, in Union, Mo. The crude new method of making methamphetamine, by combining raw and unstable ingredients in a 2-liter soda bottle, poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment _ a burden so costly that it?s contributing to the closure of some burn units. (AP Photo/Franklin County Sheriff?s Department )

This dashboard police video photo provided Jan. 17, 2012, by the Tennessee Methamphetamine Task Force shows what authorities say is a mobile shake-and-bake meth lab vehicle burning in August, 2011, in Clarksville, Tenn. The crude new method of making methamphetamine, by combining raw and unstable ingredients in a 2-liter soda bottle, poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment _ a burden so costly that it?s contributing to the closure of some burn units. (AP Photo/Tennessee Methamphetamine Task Force)

This photo provided Jan. 19, 2012, by the Tennessee Methamphetamine Task Force shows shows the interior of a home in Clarksville, Tenn., damaged by a shake-and-bake meth lab explosion in December, 2011. The crude new method of making methamphetamine, by combining raw and unstable ingredients in a 2-liter soda bottle, poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment _ a burden so costly that it?s contributing to the closure of some burn units. (AP Photo/Tennessee Methamphetamine Task Force, Jesse Reynolds)

This photo provided Jan. 17, 2012, by the Tennessee Methamphetamine Task Force shows the aftermath what authorities say is a mobile shake-and-bake meth lab vehicle that burned in August, 2011, in Clarksville, Tenn. The crude new method of making methamphetamine, by combining raw and unstable ingredients in a 2-liter soda bottle, poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment _ a burden so costly that it?s contributing to the closure of some burn units. (AP Photo/Tennessee Methamphetamine Task Force)

ST. LOUIS (AP) ? A crude new method of making methamphetamine poses a risk even to Americans who never get anywhere near the drug: It is filling hospitals with thousands of uninsured burn patients requiring millions of dollars in advanced treatment ? a burden so costly that it's contributing to the closure of some burn units.

So-called shake-and-bake meth is produced by combining raw, unstable ingredients in a 2-liter soda bottle. But if the person mixing the noxious brew makes the slightest error, such as removing the cap too soon or accidentally perforating the plastic, the concoction can explode, searing flesh and causing permanent disfigurement, blindness or even death.

An Associated Press survey of key hospitals in the nation's most active meth states showed that up to a third of patients in some burn units were hurt while making meth, and most were uninsured. The average treatment costs $6,000 per day. And the average meth patient's hospital stay costs $130,000 ? 60 percent more than other burn patients, according to a study by doctors at a burn center in Kalamazoo, Mich.

The influx of patients is overwhelming hospitals and becoming a major factor in the closure of some burn wards. At least seven burn units across the nation have shut down over the past six years, partly due to consolidation but also because of the cost of treating uninsured patients, many of whom are connected to methamphetamine.

Burn experts agree the annual cost to taxpayers is well into the tens if not hundreds of millions of dollars, although it is impossible to determine a more accurate number because so many meth users lie about the cause of their burns.

Larger meth labs have been bursting into flame for years, usually in basements, backyard sheds or other private spaces. But those were fires that people could usually escape. Using the shake-and-bake method, drugmakers typically hold the flammable concoction up close, causing burns from the waist to the face.

"You're holding a flame-thrower in your hands," said Jason Grellner of the Franklin County, Mo., Sheriff's Department.

Also known as the "one-pot" approach, the method is popular because it uses less pseudoephedrine ? a common component in some cold and allergy pills. It also yields meth in minutes rather than hours, and it's cheaper and easier to conceal. Meth cooks can carry all the ingredients in a backpack and mix them in a bathroom stall or the seat of a car.

The improvised system first emerged several years ago, partly in response to attempts by many states to limit or forbid over-the-counter access to pseudoephedrine. Since then, the shake-and-bake recipe has spread to become the method of choice.

By 2010, about 80 percent of labs busted by the federal Drug Enforcement Administration were using shake-and-bake recipes, said Pat Johnakin, a DEA agent specializing in meth.

So instead of a large lab that supplies many users, there are now more people making meth for their personal use. The consequences are showing up in emergency rooms and burn wards.

"From what we see on the medical side, that's the primary reason the numbers seem to be going up: greater numbers of producers making smaller batches," said Dr. Michael Smock, director of the burn unit at Mercy Hospital St. Louis.

It's impossible to know precisely how many people are burned while making shake-and-bake meth. Some avoid medical treatment, and no one keeps exact track of those who go to the hospital. But many burn centers in the nation's most active meth-producing states report sharp spikes in the number of patients linked to meth. And experts say the trend goes well beyond those facilities, easily involving thousands of drug users.

The director of the burn center at Vanderbilt University in Tennessee, the state that led the nation in meth lab seizures in 2010, said meth injuries are doubly damaging because patients often suffer thermal burn from the explosion, as well as chemical burns. And the medical challenge is compounded by patients' addictions.

"You're not judgmental in this kind of work, but you see it day after day," said Vanderbilt's Dr. Jeffrey Guy. "We've had patients say, 'I'm going out for a smoke,' and they come back all jacked up. It's clear they went out and did meth again."

Few people burned by meth will admit it.

"We get a lot of people who have strange stories," said Dr. David Greenhalgh, past president of the American Burn Association and director of the burn center at the University of California, Davis. "They'll say they were working on the carburetor at 2 or 3 in the morning and things blew up. So we don't know for sure, but 25 to 35 percent of our patients are meth-positive when we check them."

Guy cited a similar percentage at Vanderbilt, which operates the largest burn unit in Tennessee. He said the lies can come with a big price because the chemicals used in meth-making are often as dangerous as the burns themselves.

He recalled the case of a woman who arrived with facial burns that she said were caused by a toaster. As a result, she didn't tell doctors that meth-making chemicals got into her eyes, delaying treatment.

"Now she's probably going to be blind because she wasn't honest about it," Guy said.

In Indiana, about three-quarters of meth busts now involve shake-and-bake. And injuries are rising sharply, mostly because of burns, said Niki Crawford of the Indiana State Police Meth Suppression Team.

Indiana had 89 meth-related injuries during the 10-year period ending in 2009. The state has had 70 in the last 23 months, mostly from shake-and-bake labs, Crawford said.

What's more, meth-related burns often sear some of the body's most sensitive areas ? the face and hands.

"I don't think a lot of these patients will be able to re-enter society, said Dr. Lucy Wibbenmeyer of the burn center at the University of Iowa. "They'll need rehab therapy, occupational therapy, which is very expensive."

Researchers at the University of Iowa found that people burned while making meth typically have longer hospital stays and more expensive bills than other burn patients ? bills that are frequently absorbed by the hospital since a vast majority of the meth-makers lack insurance.

Medicaid provides reimbursement for many patients lacking private insurance, but experts say it amounts to pennies on the dollar.

Doctors at Bronson Methodist Hospital in Kalamazoo, Mich., performed a five-year study of meth patients in the early 2000s, then a follow-up study in 2009-2010. Their investigation concurred with the Iowa findings. The Kalamazoo study also found that meth burn victims were more likely to suffer damage to the lungs and windpipe, spent more time on ventilators and needed surgery more often.

That report also found that only about 10 percent of meth patients had private insurance coverage, compared with 59 percent of other patients. And in many cases, their injuries leave them unable to work.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-01-23-Meth-Severe%20Burns/id-c0bd910f1f04435a8092acd8534b2a00

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Tuesday, January 24, 2012

Cheap Car Insurance Quotes - Investment

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Source: http://www.thefinancialpress.com/2012/01/22/cheap-car-insurance-quotes/

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Egypt's Islamists win 75 percent of parliament (AP)

CAIRO ? Final results on Saturday showed that Islamist parties won nearly three-quarters of the seats in parliament in Egypt's first elections since the ouster of authoritarian president Hosni Mubarak, according to election officials and political groups.

The Islamist domination of Egypt's parliament has worried liberals and even some conservatives about the religious tone of the new legislature, which will be tasked with forming a committee to write a new constitution. It remains unclear whether the constitution will be written while the generals who took power after Mubarak's fall are still in charge, or rather after presidential elections this summer.

In the vote for the lower house of parliament, a coalition led by the fundamentalist Muslim Brotherhood won 47 percent, or 235 seats in the 498-seat parliament. The ultraconservative Al-Nour Party was second with 25 percent, or 125 seats.

The Salafi Al-Nour, which was initially the biggest surprise of the vote, wants to impose strict Islamic law in Egypt, while the more moderate Brotherhood, the country's best-known and organized party, has said publicly that it does not seek to force its views about an appropriate Islamic lifestyle on Egyptians.

The two parties are unlikely to join forces because of ideological differences, but both have a long history of charity work in Egypt's vast poverty-stricken neighborhoods and villages, giving them a degree of legitimacy and popularity across the country in areas where newer liberal parties have yet to get a foothold.

Muslim Brotherhood lawmaker Mohammed el-Beltagi said the new parliament represents "the wish of the Egyptian people."

Egypt's elections commission acknowledged that there were voting irregularities, but the vote has been hailed as the country's freest and fairest in living memory.

The liberals who spearheaded the revolt that toppled Mubarak struggled to organize and connect with a broader public in the vote, and did not fair as well as the Islamists.

The Egyptian bloc, which is headed by a party founded by Christian telecom tycoon Naguib Sawiris, said it won 9 percent of the seats in parliament. Egypt's oldest secular party, the Wafd, also won around 9 percent.

Newer parties, such as the liberal Revolution Continues Party won 2 percent, as did the Islamist Center Party, which had been banned from politics under Mubarak.

The results leave the liberal groups with little ability to maneuver in parliament, unless they choose to mobilize the street in protests or work on key issues with the dominant Islamist groups, said Mohamed Abu-Hamed, the deputy leader of the liberal Free Egyptians Party.

The Brotherhood has refused to join recent street protests, saying that elections and the new parliament are the best ways to respond to demands that the military transfer power immediately to a civilian authority.

"The street and the parliament are not at opposite ends. The issues are not going to be resolved by protests, but through parliamentary laws," the Brotherhood's el-Beltagi said.

The final tally, which includes at least 15 seats for former regime figures, comes as little surprise since election results had been partially announced throughout the three stages of the vote, which took place over several weeks across the country.

The United States long shunned Islamist groups like the Muslim Brotherhood and turned a blind-eye to the arrest and torture of Salafis, who now comprise the bulk of Al-Nour Party's constituents, under Mubarak, who was a longtime U.S. ally.

However, top U.S. officials from the State Department have recently met with the Muslim Brotherhood's leaders, who have in turn assured Western officials that they respect minority rights and support democracy.

A White House statement said that President Barack Obama called Egypt's ruling military leader, Field Marshal Hussein Tantawi, on Friday and welcomed the historic seating of the lower house of Egypt's Parliament, which is set to convene for the first time on Monday. Activists have accused the country's military leaders of repressive tactics. Critics say the nearly 12,000 civilians who have faced military trials since Mubarak's ouster have not been afforded proper due process.

Chief military prosecutor Adel el-Morsi said that 1,959 people convicted in military courts since Mubarak's ouster would be released on the one-year anniversary of the start of the uprising on Wednesday.

Among them would be Maikel Nabil Sanad, a blogger who was arrested in March and sentenced to two years in prison on charges of criticizing the armed forces and publishing false information for comments on his blog comparing the military to Mubarak's regime.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120122/ap_on_re_mi_ea/ml_egypt

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Monday, January 23, 2012

James' passion, great range remembered (AP)

NEW YORK ? On her last album "The Dreamer," released just three months before her death, Etta James sings a mix of covers, from the R&B classic "Misty Blue" to the Ray Charles song "In the Evening." But perhaps the most curious tune included on the disc may be the Guns N' Roses staple "Welcome to the Jungle."

That a 73-year-old icon of R&B would tackle the frenetic rock song ? albeit in a pace more fitting her blues roots ? might seem odd. But the song may be the best representation of James as both a singer and a person ? rambunctious in spirit, with the ability to sing whatever was thrown at her, whether it was jazz, blues, pining R&B or a song from one of the rowdiest bands in rock.

"She was able to dig so deep in kind of such a raw and unguarded place when she sang, and that's the power of gospel and blues and rhythm and blues. She brought that to all those beautiful standards and rocks songs that she did. All the number of vast albums she recorded, she covered such a wide variety of material that brought such unique phrasing and emotional depth," said Bonnie Raitt, a close friend, in an interview on Friday afternoon after James' death.

"I think that's what appealed to people, aside from the fact that her personality on and off the stage was so huge and irrepressible. She was ribald and raunchy and dignified, classy and strong and vulnerable all at the same time, which is what us as women really relate to."

James, whose signature song was the sweeping, jazz-tinged torch song "At Last," died in Riverside, Calif., from complications of leukemia. Her death came after she struggled with dementia and other health problems, health issues that kept her from performing for the last two or so years of her life.

It was a life full of struggles. Her mother was immersed in a criminal life and left her to be raised by friends, she never knew her true father (though she believed it was billiards great Minnesota Fats), and she had her own troubles, which included a decades-long addiction to drugs, turbulent relationships, brushes with the law, and other tribulations.

One might think all of those problems would have weighted down James' spirit, and her voice, layering it with sadness, or despair. While she certainly could channel depression, anger, and sorrow in song, her voice was defined by its fiery passion: Far from beaten down, James embodied the fight of a woman who managed to claw her way back from the brink, again and again.

It's an attitude that influenced her look as well. Despite the conservative era, she dyed her hair platinum blonde, sending out the signal that she was far from demure, and owning a brassy, sassy attitude. She relished her role as saucy singer, a persona that she celebrated in her private life as well.

"In terms of 1950s rhythm and blues stars, she had kind of a gutsy attitude and she went out there and did what she did, and she was kind of bold ... and it had a huge influence," said David Ritz, the co-author of her autobiography "Rage to Survive: The Etta James Story." "I think her gutsiness and her lack of fear and just her courage (made her special). ... I believe that made her important and memorable."

Beyonce, who played James in the movie "Cadillac Records" about Chess Records, also spoke about her influence on other singers.

"I feel like Etta James, first of all, was the first black woman I saw with platinum, blonde hair. She wore her leopard and she wore her sexy silhouette and she didn't care. She was strong and confident and always Etta James," said Beyonce in a 2008 interview.

James could often be irascible. Ritz remembers when he was working with her on her autobiography, touring with her around the country, that one time he approached her with his tape recorder and she barked: "If see that tape recorder again I'm going to cram it up your (expletive)."

But at other times, she'd be effusive and warm and anxious to talk.

"Once she did talk, she was always candid and unguarded. She was a free spirit," Ritz said.

While Ritz put her in the category of other greats like Ray Charles, Aretha Franklin and Marvin Gaye, she never enjoyed their mainstream success. Though "At Last" has become an enduring classic, there were times when James had to scrounge for work, and while she won Grammys and was inducted into the Rock and Roll Hall of Fame, she did not have the riches, the multitude of platinum records or the hits that some of her peers enjoyed.

"She at least enjoyed a great resurgence like John Lee Hooker did and B.B. King, (and) has had some great decades of appreciation from new generations around the world," said Raitt. "There's no one like her. No one will ever replace Etta."

And Ritz said the lack of commercial success does nothing to diminish her greatness, or her legacy.

"Marvin certain knew it and Ray knew it ... the people who know that she was in that category," he said. "Whatever the marketplace did or didn't do or whether her lack of career management didn't do, it has nothing to do with her talent."

And on Friday, the Queen of Soul was among those who paid tribute to James greatness, calling her "one of the great soul singers of our generation. An American original!

"I loved `Pushover,' `At Last' and almost any and everything she recorded! When Etta SUNG, you heard it!"

___

AP Entertainment Writer Chris Talbott and AP Writer Mesfin Fekadu contributed to this report.

___

Nekesa Mumbi Moody is the AP's music editor. Follow her at http://www.twitter.com/nekesamumbi

Source: http://us.rd.yahoo.com/dailynews/rss/celebrity/*http%3A//news.yahoo.com/s/ap/20120121/ap_en_ce/us_etta_james_appreciation

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If feds can bust Megaupload, why bother with anti-piracy bills?

A growing battle over copyright on the internet came to a head this week as digital protests scuttled two anti-piracy bills, police arrested Megaupload's millionaire filesharing pirate, and hackers brought down the Department of Justice website.

It was almost as if the thrums of digital artillery could be felt across millions of keyboards.

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As some of the internet's biggest power players, including Google and Wikipedia, protested two fast-tracked anti-piracy bills going through Congress, the US Justice Department launched an attack on one of the web's biggest alleged scofflaws, Megaupload, and, in a counterattack, the hacker group Anonymous temporarily blacked out DOJ's website.

Techno-pundits and mainstream observers quickly connected the dots between anti-piracy protests and the Megaupload arrests, notching the dustup as potentially the biggest salvo yet in the multi-billion dollar internet copyright wars pitting, in essence, Hollywood and its Washington lobbyists against internet free speech and its hacker protectors.

RECOMMENDED:?How five websites are protesting SOPA

?This week has been?the?week of copyright warfare, but the decision to nuke the king copyright violator so spectacularly only goes to show how little the feds need bigger bombs,? writes Sam Biddle on the tech-scene site Gizmodo.

The Justice Department has not commented on the timing of its arrest of Kim Dotcom (also known as Kim Schmitz), the high-flying millionaire CEO of Megaupload, who is now in custody and being prepared for extradition to the United States from his home base of Auckland, New Zealand. The arrests came after a two year investigation.

Megaupload was perhaps the most brazen of dozens of file-sharing sites, offering cash for particularly lucrative uploads and partnering with some big-name rappers in its barely-concealed bid to dispense and disperse pirated music and film. The site has 150 million members and makes up 4 percent of all daily traffic on the web.

But the decision by the Justice Department to net such a big, obvious fish at this time raised eyebrows among the internet cognoscenti, who posited that it was meant as a retort to populist digital forces that amassed in protest of the fast-tracking of two anti-piracy bills, the Stop Online Piracy Act (SOPA) and Preventing Real Online Threats to Economic Creativity and Theft of Intellectual Property Act (PIPA). Citing the protests, Congressional leaders forestalled the bills on Friday, saying they need more work.

Championed by the Motion Picture Association of America and the Chamber of Commerce, the anti-piracy bills would have broadened the Justice Department's justifications for seeking court orders against alleged copyright violators, prevented advertisers from doing business with such sites, banned search engines from listing them, and forced internet service providers to block the sites.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/gh_XxumdhIA/If-feds-can-bust-Megaupload-why-bother-with-anti-piracy-bills

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Sunday, January 22, 2012

'Extinct' monkey rediscovered in Borneo by new expedition

Friday, January 20, 2012

An international team of scientists has found one of the rarest and least known primates in Borneo, Miller's Grizzled Langur, a species which was believed to be extinct or on the verge of extinction. The team's findings, published in the American Journal of Primatology, confirms the continued existence of this endangered monkey and reveals that it lives in an area where it was previously not known to exist.

Miller's Grizzled Langur (Presbytis hosei canicrus) is part of the small primate genus Presbytis, found across Borneo, Sumatra, Java and the Thai-Malay Peninsula. In Borneo, P.h. canicrus is only found in a small corner of the county's north east and its habitat has suffered from fires, human encroachment and conversion of land for agriculture and mining.

The team's expedition took to them to Wehea Forest in East Kalimantan, Borneo, a large 38,000 ha area of mostly undisturbed rainforest. Wehea contains at least nine known species of non-human primate, including the Bornean orangutan and gibbon.

"Discovery of P.h canicrus was a surprise since Wehea Forest lies outside of this monkey's known range. Future research will focus on estimating the population density for P.h. canicrus in Wehea and the surrounding forest," said Brent Loken, from Simon Fraser University Canada. "Concern that the species may have gone extinct was first raised in 2004, and a search for the monkey during another expedition in 2008 supported the assertion that the situation was dire."

By conducting observations at mineral licks where animals congregate and setting up camera traps in several locations, the expedition confirmed that P. h canicrus continues to survive in areas west of its previously recorded geographic range. The resulting photos provide the first solid evidence demonstrating that its geographic range extends further than previously thought.

"It was a challenge to confirm our finding as there are so few pictures of this monkey available for study," said Loken. "The only description of Miller's Grizzled Langur came from museum specimens. Our photographs from Wehea are some of the only pictures that we have of this monkey."

"East Kalimantan can be a challenging place to conduct research, given the remoteness of many remaining forested areas, so it isn't surprising that so little is known about this primate," said Dr. Stephanie Spehar, Assistant Professor of Anthropology at University of Wisconsin Oshkosh. "We are very grateful to our local partners. This discovery represents the hard work, dedication, and collaboration of Western and Indonesian scientists, students, NGOs, as well as local communities and government."

"While our finding confirms the monkey still exists in East Kalimantan, there is a good chance that it remains one of the world's most endangered primates," concluded Loken. "I believe it is a race against time to protect many species in Borneo. It is difficult to adopt conservation strategies to protect species when we don't even know the extent of where they live. We need more scientists in the field working on understudied species such as Miller's Grizzled Langur, clouded leopards and sun bears."

###

Wiley-Blackwell: http://www.wiley.com/wiley-blackwell

Thanks to Wiley-Blackwell for this article.

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Source: http://www.labspaces.net/116909/_Extinct__monkey_rediscovered_in_Borneo_by_new_expedition

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Saturday, January 21, 2012

Aspirin merits testing for prevention of cervical cancer in HIV-infected women

Thursday, January 19, 2012

Research conducted by NewYork-Presbyterian Hospital/Weill Cornell Medical Center global health investigators and cancer specialists in New York, Qatar and Haiti suggests that aspirin should be evaluated for its ability to prevent development of cervical cancer in HIV-infected women.

The report, published in the current issue of journal Cancer Prevention Research, says this simple and inexpensive solution has the potential to provide enormous benefit for women in the Caribbean, Latin America and Africa, who suffer from a disproportionately high rate of cervical cancer death.

Preventive aspirin use could be especially useful in Haiti, where invasive cervical cancer is a common cause of death in HIV-infected women. The country also has the highest reported incidence of cervical cancer in the world and one of the highest HIV infection rates in the Western Hemisphere.

"These young patients -- many of whom were mothers and the sole support for their families -- had worked hard to have their HIV controlled with antiretroviral therapy, only to develop and die from cervical cancer," says the study's lead researcher, Dr. Daniel Fitzgerald, an associate professor of medicine at Weill Cornell Medical College who lived in Haiti for seven years and continues to treat HIV patients there.

Dr. Fitzgerald is a key member of the Weill Cornell Medical College Center for Global Health and directs the College's collaboration with GHESKIO, a Haitian non-governmental organization dedicated to providing clinical service, research and training in HIV/AIDS since 1980.

"The results of this collaborative effort will make a real difference for women living in one of the poorest nations in the world," he says. "It is wonderful that clinicians and scientists from different parts of the world were able to come together to address such a critical issue of care."

The researchers discovered that HIV induces expression of the COX-2/prostaglandin E2 (PGE2) inflammatory pathway in cervical tissue samples from Haitian women who were infected with HIV. The findings tie two known facts together: that HIV causes chronic inflammation; and that PGE2, which is elevated during inflammation, is linked to cancer development in a number of tumor types, including cervical cancer.

The fact that HIV ramps up production of PGE2 in cervical tissue was not known before this study, the researchers say.

This may help explain why HIV-positive women are five times more likely to develop invasive cervical cancer than HIV-negative women. It also suggests that inhibitors of the COX-2 molecule (which contributes to the production of PGE2) might break the link between HIV and cervical cancer. Aspirin is one of the cheapest and most effective COX inhibitors.

"The findings in this study provide new insights into the link between viral infection and inflammation, two known drivers of cancer development," says senior author Dr. Andrew Dannenberg, director of the Weill Cornell Cancer Center at NewYork-Presbyterian/Weill Cornell and the Henry R. Erle, M.D.?Roberts Family Professor of Medicine at Weill Cornell Medical College.

"Future studies will be needed to determine whether aspirin-like agents, known inhibitors of prostaglandin production, can reduce the risk of cervical cancer in this high-risk population," he adds.

The researchers examined levels of COX-2 and PGE-M (a stable metabolite of PGE2) in three groups of women and found increased levels of both molecules in 13 women who were co-infected with HIV and HPV. COX-2 and PGE-M were also elevated in 18 HIV-infected women with a negative HPV test and lowest in 17 HIV-negative women who also were not infected with HPV.

The findings thus demonstrate that HIV infection is associated with increased cervical COX-2 and elevated systemic PGE2 levels, says Dr. Fitzgerald. Co-infection with HPV adds to the cervical cancer risk. Future studies will seek to define the population of women that may benefit from daily use of aspirin or related inhibitors.

Dr. Fitzgerald, along with GHESKIO physician and study co-author Dr. Cynthia Riviere, initiated the clinical research program to care for and prevent cervical cancer in HIV-positive women in Haiti after they began noticing an increasing report of cases.

"The goal is to give patients in Haiti the same standard of treatment found in any cancer center," says Dr. Jeremie Arash Rafii Tabrizi, assistant professor of genetic medicine at Weill Cornell Medical College in Qatar who has treated women at the GHESKIO clinic. "We are focusing on procedures that will allow for a reduction of morbidity -- as this is a major concern in this population -- as well as a reduction of risk of recurrence."

###

New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College: http://www.med.cornell.edu

Thanks to Weill Cornell Medical Center/Weill Cornell Medical College for this article.

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Source: http://www.labspaces.net/116842/Aspirin_merits_testing_for_prevention_of_cervical_cancer_in_HIV_infected_women

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North Korea credits new leader with nuke testing (AP)

PYONGYANG, North Korea ? North Korea on Friday credited new leader Kim Jong Un with spearheading past nuclear testing, as it adds to a growing personality cult that portrays the young son of late leader Kim Jong Il as a confident military commander.

Kim Jong Un's youth ? he's believed to be in his late 20s ? and quick rise have spurred questions in foreign capitals about his readiness for leadership. But North Korea has dismissed such worries in recent days, saying Kim Jong Un worked closely with his father on military and economic matters.

The North's official Uriminzokkiri website said Friday that Kim "frightened" the country's enemies by commanding nuclear testing in the past. North Korea tested nuclear devices in 2006 and 2009, but the website didn't specify which tests Kim oversaw.

Uriminzokkiri described Kim Jong Un as "fully equipped" with the qualities of an extraordinary general, even during his years at Kim Il Sung Military University. The website also repeated the North's claim that he was involved in satellite launching but didn't elaborate.

North Korea's linking of Kim Jong Un to past nuclear testing comes as it pushes for the resumption of long-stalled six-nation aid-for-nuclear disarmament talks that also include China, Japan, Russia, South Korea and the United States. Washington and its allies want the North to first show it is serious about previous disarmament commitments.

North Korea last week questioned Washington's generosity and sincerity, but suggested it remains open to suspending its uranium enrichment program if it can get the food aid it wants.

Kim Jong Un took over after his father and longtime ruler Kim Jong Il died in mid-December and has quickly been given many of the country's most important titles.

He was introduced as heir only in September 2010. Before that he had been kept out of the public eye for most of his life. He was quickly promoted to four-star general and named a vice chairman of the Central Military Commission of the Workers' Party of Korea.

Some of North Korea's neighbors and Washington have expressed worry about whether he can lead a nation of 24 million with a nuclear program as well as chronic trouble feeding all its people.

Kim Jong Il had 20 years of training under his own father, Kim Il Sung, before taking over. Even after his father's 1994 death, Kim Jong Il observed a three-year mourning period before formally assuming leadership.

A senior official told The Associated Press recently that Kim Jong Un spent years working closely with his late father and helped him make key policy decisions on economic and military affairs.

North Korea has also made it clear that Kim Jong Un will continue Kim Jong Il's "songun," or military-first, policy, and a steady stream of reports and images from state media has sought to show him as a fearless military commander who is comfortable with leadership.

North Korea also reported Friday that Kim Jong Un inspected two more military units.

Earlier this month, North Korea's state-run broadcaster aired a documentary that showed Kim Jong Un observing an April 2009 launch of a long-range rocket. It was the first indication of his involvement in the launch.

The documentary quoted Kim as threatening to wage war against any nation attempting to intercept the rocket, which North Korea claimed was carrying a communications satellite but the United States, South Korea and Japan said was really a test of its long-range missile technology.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20120120/ap_on_re_as/as_nkorea_kim_jong_un

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Friday, January 20, 2012

Verizon to light up five new LTE markets on Jan. 19

Verizon LTE

It's that time of month again: Verizon says it will flip the LTE switch in five new markets tomorrow, while expanding coverage in three existing areas. New to the LTE game are:

  • Glens Falls, N.Y.
  • Utica, N.Y.
  • Lawton, Okla.
  • Brownsville, Texas
  • McAllen, Texas

Those markets soon to see stronger and more widespread LTE signals include:

  • Atlanta, Ga.
  • Houston, Texas
  • Spokane, Wash.

For those keeping count, this brings the total number of markets covered by Verizon's LTE service up to 195. (Plus, Peoria's still somewhat live.) Hit the source link for Verizon's full presser, which includes a handy list of all live markets.

Source: Verizon Wireless



Source: http://feedproxy.google.com/~r/androidcentral/~3/NaFLqIYhdkU/story01.htm

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